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MRCPUK SEND Exam Syllabus Topics:
| Section | Objectives |
|---|---|
| Topic 1: Calcium and Bone Metabolism | - Parathyroid and Metabolic Bone Disease
|
| Topic 2: Pituitary and Hypothalamic Disorders | - Pituitary Disease
|
| Topic 3: Thyroid Disorders | - Thyroid Disease
|
| Topic 4: General Endocrinology | - Integrated Clinical Practice
|
| Topic 5: Diabetes Mellitus | - Complications
|
| Topic 6: Reproductive Endocrinology | - Gonadal Disorders
|
| Topic 7: Adrenal Disorders | - Adrenal Disease
|
MRCPUK Endocrinology and Diabetes (Specialty Certificate Examination) Sample Questions:
A 17-year-old boy had panhypopituitarism, including diabetes insipidus, following treatment for a craniopharyngioma. He was taking appropriate replacement therapy. In the transition clinic, he was keen to continue growth hormone replacement therapy following a 12-month break after reaching final height.
Which is the most appropriate test to assess his growth hormone status?
- A. growth hormone day profile
- B. clonidine test
- C. insulin-like growth factor-binding protein 3
- D. insulin tolerance test
- E. insulin-like growth factor 1
Correct Answer: E 🗳️
A 23-year-old man presented with a history of discomfort with his gender for as long as he could remember. He believed he was transsexual.
What element of further history would most strongly support his self-diagnosis?
- A. the presence of gender somatic delusions that emerge and strengthen with time
- B. a long-standing intense wish to make his body conform to that of the preferred gender
- C. sexual excitement by cross-dressing
- D. conscious and absolute rejection of his sexual orientation as socially unacceptable
- E. seeking medical rationalisation for sexuality through genital surgery
Correct Answer: B 🗳️
A 24-year-old woman was referred with an 18-month history of worsening hirsutism, primarily on her face, but also new hair growth on her chest. She was shaving weekly. She had always been overweight, but had recently gained 5 kg and her body mass index was 31 kg/m2 (18-25). Her periods were regular.
What is the most relevant next investigation?
- A. serum dehydroepiandrosterone
- B. overnight dexamethasone suppression test (after 1 mg dexamethasone)
- C. serum 17-hydroxyprogesterone
- D. serum testosterone
- E. plasma thyroid-stimulating hormone
Correct Answer: D 🗳️
Five patients were referred to a rapid access thyroid clinic. Only four slots were available in the following month.
Which patient can safely be deferred to a later clinic?
- A. 45-year-old woman with a rapidly enlarging painless goitre
- B. 39-year-old woman with a slowly growing thyroid lump and a palpable cervical lymph node
- C. 44-year-old woman with a history of sudden-onset pain in a thyroid lump
- D. 16-year-old boy with a thyroid nodule
- E. 67-year-old man with a goitre and hoarseness
Correct Answer: C 🗳️
A 47-year-old nuclear physics professor was referred for advice before taking up an overseas position, overseeing the dismantling of a reactor at the site of a recent nuclear accident. She stated that she would face a small risk of being exposed to significant radioactive contamination during her work and was concerned about her future risk of thyroid cancer.
What is the most appropriate advice?
- A. avoid consuming local milk and vegetables
- B. take selenium tablets
- C. no precautions are necessary for people aged 40 years or over
- D. take potassium iodide tablets
- E. wear lead neck shield while outdoors
Correct Answer: D 🗳️
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